dor_id: 4149142

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650.#.4.x: Biología y Química

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: https://revistas.unam.mx/index.php/biocyt

351.#.#.b: BIOCYT. Biología, Ciencia y Tecnología

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

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856.4.0.u: https://revistas.unam.mx/index.php/biocyt/article/view/76146/67232

100.1.#.a: Ortiz Ortega, Ricardo; Martínez Elizalde, Karla S.; Villamar Duque, Tomás Ernesto

524.#.#.a: Ortiz Ortega, Ricardo, et al. (2015). TERATOGENIC EFFECT OF HERBICIDE GLIFONOX IN RATTUS NORVEGICUS, WISTAR STRAIN. BIOCYT Biología Ciencia y Tecnología; Vol. 8, 2015. Recuperado de https://repositorio.unam.mx/contenidos/4149142

245.1.0.a: TERATOGENIC EFFECT OF HERBICIDE GLIFONOX IN RATTUS NORVEGICUS, WISTAR STRAIN

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Estudios Superiores Iztacala, UNAM

264.#.0.c: 2015

264.#.1.c: 2020-06-23

653.#.#.a: Teratogenic; liver; GPT; GOT; glyphosate; isopropylamine

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY-NC-ND 4.0 Internacional, https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico hvazquez@unam.mx

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041.#.7.h: spa

520.3.#.a: Teratogenic effect of herbicide glyphosate-Roundup, sold under the name Glifotox on Wistar rats was evaluated. The biological material was treated intraperitoneally with glyphosate at concentrations of 100, 125, and 150 mg/kg from gestation day nine. Hysterectomy was performed on day 18 of gestation, and the uterine horns where the embryos were located, in addition to recording the percentage of malformed embryos by modifying the method of Wilson were observed. The liver was removed and quantified by spectrophotometry with transaminase activity showed higher concentrations malformation rate and higher enzyme activity was 125 mg/kg, below is the average of 100 mg/kg and higher concentrations such as 150 mg/kg a large number of resorptions was obtained. It is concluded that glyphosate is toxic affecting the liver and liver enzymes involved in the formation of amino acids also produce delay in embryonic development.

773.1.#.t: BIOCYT Biología Ciencia y Tecnología; Vol. 8 (2015)

773.1.#.o: https://revistas.unam.mx/index.php/biocyt

022.#.#.a: ISSN electrónico: 2007-2082

310.#.#.a: Publicación contínua

264.#.1.b: Facultad de Estudios Superiores Iztacala, UNAM

doi: https://doi.org/10.22201/fesi.20072082e.2015.8.76146

harvesting_date: 2023-11-08 13:10:00.0

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file_creation_date: 2015-10-07 20:36:28.0

file_modification_date: 2015-10-07 20:36:28.0

file_creator: Horacio Vázquez López

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Artículo

TERATOGENIC EFFECT OF HERBICIDE GLIFONOX IN RATTUS NORVEGICUS, WISTAR STRAIN

Ortiz Ortega, Ricardo; Martínez Elizalde, Karla S.; Villamar Duque, Tomás Ernesto

Facultad de Estudios Superiores Iztacala, UNAM, publicado en BIOCYT. Biología, Ciencia y Tecnología, y cosechado de Revistas UNAM

Licencia de uso

Procedencia del contenido

Cita

Ortiz Ortega, Ricardo, et al. (2015). TERATOGENIC EFFECT OF HERBICIDE GLIFONOX IN RATTUS NORVEGICUS, WISTAR STRAIN. BIOCYT Biología Ciencia y Tecnología; Vol. 8, 2015. Recuperado de https://repositorio.unam.mx/contenidos/4149142

Descripción del recurso

Autor(es)
Ortiz Ortega, Ricardo; Martínez Elizalde, Karla S.; Villamar Duque, Tomás Ernesto
Tipo
Artículo de Investigación
Área del conocimiento
Biología y Química
Título
TERATOGENIC EFFECT OF HERBICIDE GLIFONOX IN RATTUS NORVEGICUS, WISTAR STRAIN
Fecha
2020-06-23
Resumen
Teratogenic effect of herbicide glyphosate-Roundup, sold under the name Glifotox on Wistar rats was evaluated. The biological material was treated intraperitoneally with glyphosate at concentrations of 100, 125, and 150 mg/kg from gestation day nine. Hysterectomy was performed on day 18 of gestation, and the uterine horns where the embryos were located, in addition to recording the percentage of malformed embryos by modifying the method of Wilson were observed. The liver was removed and quantified by spectrophotometry with transaminase activity showed higher concentrations malformation rate and higher enzyme activity was 125 mg/kg, below is the average of 100 mg/kg and higher concentrations such as 150 mg/kg a large number of resorptions was obtained. It is concluded that glyphosate is toxic affecting the liver and liver enzymes involved in the formation of amino acids also produce delay in embryonic development.
Tema
Teratogenic; liver; GPT; GOT; glyphosate; isopropylamine
Idioma
spa
ISSN
ISSN electrónico: 2007-2082

Enlaces