La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY-NC-ND 4.0 Internacional, https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico revistatip@yahoo.com.
Ver términos de la licenciaCarrillo Martínez, José Carlos, et al. (2023). Synthetic biology: On the development of genetic circuits and their potential applications in biosciences and biofuels. TIP Revista Especializada en Ciencias Químico-Biológicas; Vol. 26, 2023. Recuperado de https://repositorio.unam.mx/contenidos/4158424
Autor(es)
Carrillo Martínez, José Carlos; Díaz Zaragoza, Mariana; Oceguera Contreras, Edén; Ortiz Torres, Gerardo
Tipo
Artículo de Investigación
Área del conocimiento
Biología y Química
Título
Synthetic biology: On the development of genetic circuits and their potential applications in biosciences and biofuels
Fecha
2023-03-14
Resumen
Synthetic biology aims to develop cells with entirely new functions not found in nature. These functions are manifested through pathways created of genes from other microorganisms linked by molecular techniques such as Bio-Brick Assembly. Some of these linkages can adopt a Boolean behavior and generate what is known as a genetic circuit that is mainly composed of the functional parts of a gene (Promoter, RBS, ORF, Terminator). These interchangeable parts form what is called a Bio-Brick, which can act as a logical gateway by showing an excellent stability and the activation of genetic memory that can lasts after several generations. As a result of the different types of behavior that Bio-Bricks present, they are highly attractive for the industry because it would be enough to choose the best type of circuit for multiple applications both in the biomedical industry (cancer drugs, malaria, specific antibodies, microbiome engineering) or the energy industry in order to produce second-generation biofuels that can compete effectively with fossil fuels; it has also been discovered that due to its usefulness in different fields, it represents a solution to problems such as high greenhouse gas emissions or the current pandemic caused by the appearance of the SARS-CoV-2 virus.
Tema
Biología Sintética; Circuitos Genéticos; Bio-bricks; Ingeniería Del Microbioma; Rutas Sintéticas; Producción De Biocombustibles; Synthetic Biology; Genetic Circuits; Bio-brick; Microbiome Engineering; Synthetic Pathways; Biofuel
Idioma
spa
ISSN
ISSN electrónico: 2395-8723; ISSN impreso: 1405-888X
