dor_id: 4122053

506.#.#.a: Público

590.#.#.d: Los artículos enviados a la revista "Veterinaria México OA", se juzgan por medio de un proceso de revisión por pares

510.0.#.a: Consejo Nacional de Ciencia y Tecnología (CONACyT); Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex); Scientific Electronic Library Online (SciELO); Bibliografía Latinoamericana (Biblat); La Red de Revistas Científicas de América Latina y el Caribe, España y Portugal (Redalyc); Connecting research and researchers (ORCiD)

561.#.#.u: https://www.fmvz.unam.mx/

650.#.4.x: Biotecnología y Ciencias Agropecuarias

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

351.#.#.b: Veterinaria México OA

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

590.#.#.c: Open Journal Systems (OJS)

270.#.#.d: MX

270.1.#.d: México

590.#.#.b: Concentrador

883.#.#.u: https://revistas.unam.mx/catalogo/

883.#.#.a: Revistas UNAM

590.#.#.a: Coordinación de Difusión Cultural

883.#.#.1: https://www.publicaciones.unam.mx/

883.#.#.q: Dirección General de Publicaciones y Fomento Editorial

850.#.#.a: Universidad Nacional Autónoma de México

856.4.0.u: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/560/590

100.1.#.a: Maciel Rivera, Anaid; Flores Villalva, Susana; Jímenez Vázquez, Itzel; Catalán Barcenas, Omar; Espitia Pinzón, Clara Inés; Morán, Julio; Arriaga Pizano, Lourdes; Benítez Guzmán, Alejandro; Alfonseca Silva, Edgar; Gutiérrez Pabello, José Ángel

524.#.#.a: Maciel Rivera, Anaid, et al. (2019). Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages. Veterinaria México OA; Vol. 6 Núm. 1, 2019. Recuperado de https://repositorio.unam.mx/contenidos/4122053

245.1.0.a: Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Medicina Veterinaria y Zootecnia, UNAM

264.#.0.c: 2019

264.#.1.c: 2019-03-22

653.#.#.a: M. bovis; M. tuberculosis; bovine macrophages; caspase

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY 4.0 Internacional, https://creativecommons.org/licenses/by/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico vetmexicooa@gmail.com

884.#.#.k: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/560

001.#.#.#: 131.oai:ojs.pkp.sfu.ca:article/560

041.#.7.h: eng

520.3.#.a: Species of the genus mycobacterium are capable of inducing cell apoptosis. infected cells with m. tuberculosis undergo apoptosis through a caspase-dependent pathway. we have previously shown that whole mycobacterium bovis cells and derived crude protein extracts were able to trigger apoptosis through a caspase independent mechanism. however, the identity of the protein or protein fractions capable of inducing apoptosis has not been determined. in this study, bovine macrophages were incubated in the presence of mycobacterium tuberculosis recombinant proteins and mycobacterium bovis protein extracts to identify proteins capable of inducing apoptosis. A subgroup of proteins and protein extracts from strains of the mycobacterium tuberculosis complex were shown to induce dna fragmentation in bovine macrophages through a caspase independent pathway. our findings suggest that bovine macrophages may elicit a different response to mycobacterium infection than that displayed by murine or human cells.

773.1.#.t: Veterinaria México OA; Vol. 6 Núm. 1 (2019)

773.1.#.o: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

022.#.#.a: ISSN electrónico: 2448-6760

310.#.#.a: Trimestral

264.#.1.b: Facultad de Medicina Veterinaria y Zootecnia, UNAM

doi: https://doi.org/10.22201/fmvz.24486760e.2019.1.560

harvesting_date: 2023-11-08 13:10:00.0

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Artículo

Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages

Maciel Rivera, Anaid; Flores Villalva, Susana; Jímenez Vázquez, Itzel; Catalán Barcenas, Omar; Espitia Pinzón, Clara Inés; Morán, Julio; Arriaga Pizano, Lourdes; Benítez Guzmán, Alejandro; Alfonseca Silva, Edgar; Gutiérrez Pabello, José Ángel

Facultad de Medicina Veterinaria y Zootecnia, UNAM, publicado en Veterinaria México OA, y cosechado de Revistas UNAM

Licencia de uso

Procedencia del contenido

Entidad o dependencia
Facultad de Medicina Veterinaria y Zootecnia, UNAM
Revista
Veterinaria México OA
Repositorio
Revistas UNAM
Contacto
Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

Cita

Maciel Rivera, Anaid, et al. (2019). Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages. Veterinaria México OA; Vol. 6 Núm. 1, 2019. Recuperado de https://repositorio.unam.mx/contenidos/4122053

Descripción del recurso

Autor(es)
Maciel Rivera, Anaid; Flores Villalva, Susana; Jímenez Vázquez, Itzel; Catalán Barcenas, Omar; Espitia Pinzón, Clara Inés; Morán, Julio; Arriaga Pizano, Lourdes; Benítez Guzmán, Alejandro; Alfonseca Silva, Edgar; Gutiérrez Pabello, José Ángel
Tipo
Artículo de Investigación
Área del conocimiento
Biotecnología y Ciencias Agropecuarias
Título
Mycobacterium tuberculosis and Mycobacterium bovis derived proteins induce caspase-independent apoptosis in bovine macrophages
Fecha
2019-03-22
Resumen
Species of the genus mycobacterium are capable of inducing cell apoptosis. infected cells with m. tuberculosis undergo apoptosis through a caspase-dependent pathway. we have previously shown that whole mycobacterium bovis cells and derived crude protein extracts were able to trigger apoptosis through a caspase independent mechanism. however, the identity of the protein or protein fractions capable of inducing apoptosis has not been determined. in this study, bovine macrophages were incubated in the presence of mycobacterium tuberculosis recombinant proteins and mycobacterium bovis protein extracts to identify proteins capable of inducing apoptosis. A subgroup of proteins and protein extracts from strains of the mycobacterium tuberculosis complex were shown to induce dna fragmentation in bovine macrophages through a caspase independent pathway. our findings suggest that bovine macrophages may elicit a different response to mycobacterium infection than that displayed by murine or human cells.
Tema
M. bovis; M. tuberculosis; bovine macrophages; caspase
Idioma
eng
ISSN
ISSN electrónico: 2448-6760

Enlaces