dor_id: 59063

506.#.#.a: Público

590.#.#.d: Los artículos enviados a la "Revista Mexicana de Ortodoncia", se juzgan por medio de un proceso de revisión por pares

510.0.#.a: Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex); Medigraphic

561.#.#.u: http://www.odonto.unam.mx/

561.#.#.a: Facultad de Odontología, UNAM

650.#.4.x: Medicina y Ciencias de la Salud

336.#.#.b: article

336.#.#.3: Artículo Técnico-Profesional

336.#.#.a: Artículo

351.#.#.6: https://revistas.unam.mx/index.php/rmo

351.#.#.b: Revista Mexicana de Ortodoncia

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

590.#.#.c: Open Journal Systems (OJS)

270.#.#.d: MX

270.1.#.d: México

590.#.#.b: Concentrador

883.#.#.u: https://revistas.unam.mx/catalogo/

883.#.#.a: Revistas UNAM

590.#.#.a: Coordinación de Difusión Cultural

883.#.#.1: https://www.publicaciones.unam.mx/

883.#.#.q: Dirección General de Publicaciones y Fomento Editorial

850.#.#.a: Universidad Nacional Autónoma de México

856.4.0.u: https://revistas.unam.mx/index.php/rmo/article/view/63314/55600

100.1.#.a: López González, Carolina; Maldonado Martínez, Héctor Aquiles; García López, Salvador; Rosas Ramírez, María Del Carmen; López Casillas, Fernando; Pérez González, Araceli; Gutiérrez Valdez, Dulce Haydeé

524.#.#.a: López González, Carolina, et al. (2017). Immunoexpression of transforming growth factor-β3 (TGF-β3) and receptor III of β transforming growth factor (TGF β-RIII) in pediatric patients with complete or incomplete non-syndromic cleft palate. Revista Mexicana de Ortodoncia; Vol. 5 Núm. 4, 2017. Recuperado de https://repositorio.unam.mx/contenidos/59063

720.#.#.a: García López, Salvador ; Maldonado Martínez, Héctor Aquiles ; Gutiérrez Valdez, Dulce Haydeé ; López Casillas, Fernando ; Rosas Ramírez, María Del Carmen ; Pérez González, Araceli ; López González, Carolina

245.1.0.a: Immunoexpression of transforming growth factor-β3 (TGF-β3) and receptor III of β transforming growth factor (TGF β-RIII) in pediatric patients with complete or incomplete non-syndromic cleft palate

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Odontología, UNAM

264.#.0.c: 2017

264.#.1.c: 2018-02-06

653.#.#.a: Cleft palate; transforming growth factor β3; receptor III of transforming growth factor β

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY-NC-ND 4.0 Internacional, https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico revistamexicanadeortodoncia@gmail.com

884.#.#.k: https://revistas.unam.mx/index.php/rmo/article/view/63314

001.#.#.#: 120.oai:ojs.pkp.sfu.ca:article/63314

041.#.7.h: spa

520.3.#.a: Introduction: Transforming growth factor β3 (TGF-β3), and receptor III of transforming growth factor β (TGFβ-RIII), regulate epithelial mesenchymal interactions. The lack of TGF-β3 and TGFβ-RIII expression causes defects in palatal fusion. Objective: To observe the immunoexpression of TGF-β3 and TGFβ-RIII in pediatric patients with non-syndromic complete or incomplete cleft palate (CP). Material and methods: The study design was observational, descriptive, prospective and transversal. Samples were taken from 20 complete and incomplete CP patients from five to 28 months of age. Samples of mucoperiostium were removed from the cleft in the palate during palatoplasty. In order to perform immunohistochemistry, samples were processed with VENTANA BenchMark Ultra equipment, using TGF-β3 and TGFβ-RIII antibody. Immunoexpression was evaluated by means of global cell impression. Results: TGF-β3 immunoexpression was greater in epithelial cells than in fi broblasts of patients with complete and incomplete CP; however, TGFβ-RIII immunoexpression was greater within the fi broblasts than in epithelial cells of patients with complete cleft palate. Conclusions: It was concluded that the lack of TGFβ-RIII expression in the epithelium may be related to the lack of fusion of the palatal shelves. It would be of great interest to perform a more in-depth analysis of the expressions of TGF-β3 and TGFβ-RIII within different cell populations.

773.1.#.t: Revista Mexicana de Ortodoncia; Vol. 5 Núm. 4 (2017)

773.1.#.o: https://revistas.unam.mx/index.php/rmo

022.#.#.a: ISSN: 2395-9215

310.#.#.a: Trimestral

264.#.1.b: Facultad de Odontología, UNAM

doi: https://doi.org/10.1016/j.rmo.2018.01.012

handle: 00dfc85085672727

harvesting_date: 2023-06-20 16:00:00.0

856.#.0.q: application/pdf

last_modified: 2023-06-20 16:00:00

license_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es

license_type: by-nc-nd

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No entro en nada

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Artículo

Immunoexpression of transforming growth factor-β3 (TGF-β3) and receptor III of β transforming growth factor (TGF β-RIII) in pediatric patients with complete or incomplete non-syndromic cleft palate

López González, Carolina; Maldonado Martínez, Héctor Aquiles; García López, Salvador; Rosas Ramírez, María Del Carmen; López Casillas, Fernando; Pérez González, Araceli; Gutiérrez Valdez, Dulce Haydeé

Facultad de Odontología, UNAM, publicado en Revista Mexicana de Ortodoncia, y cosechado de Revistas UNAM

Licencia de uso

Procedencia del contenido

Entidad o dependencia
Facultad de Odontología, UNAM
Revista
Revista Mexicana de Ortodoncia
Repositorio
Revistas UNAM
Contacto
Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

Cita

López González, Carolina, et al. (2017). Immunoexpression of transforming growth factor-β3 (TGF-β3) and receptor III of β transforming growth factor (TGF β-RIII) in pediatric patients with complete or incomplete non-syndromic cleft palate. Revista Mexicana de Ortodoncia; Vol. 5 Núm. 4, 2017. Recuperado de https://repositorio.unam.mx/contenidos/59063

Descripción del recurso

Autor(es)
López González, Carolina; Maldonado Martínez, Héctor Aquiles; García López, Salvador; Rosas Ramírez, María Del Carmen; López Casillas, Fernando; Pérez González, Araceli; Gutiérrez Valdez, Dulce Haydeé
Colaborador(es)
García López, Salvador ; Maldonado Martínez, Héctor Aquiles ; Gutiérrez Valdez, Dulce Haydeé ; López Casillas, Fernando ; Rosas Ramírez, María Del Carmen ; Pérez González, Araceli ; López González, Carolina
Tipo
Artículo Técnico-Profesional
Área del conocimiento
Medicina y Ciencias de la Salud
Título
Immunoexpression of transforming growth factor-β3 (TGF-β3) and receptor III of β transforming growth factor (TGF β-RIII) in pediatric patients with complete or incomplete non-syndromic cleft palate
Fecha
2018-02-06
Resumen
Introduction: Transforming growth factor β3 (TGF-β3), and receptor III of transforming growth factor β (TGFβ-RIII), regulate epithelial mesenchymal interactions. The lack of TGF-β3 and TGFβ-RIII expression causes defects in palatal fusion. Objective: To observe the immunoexpression of TGF-β3 and TGFβ-RIII in pediatric patients with non-syndromic complete or incomplete cleft palate (CP). Material and methods: The study design was observational, descriptive, prospective and transversal. Samples were taken from 20 complete and incomplete CP patients from five to 28 months of age. Samples of mucoperiostium were removed from the cleft in the palate during palatoplasty. In order to perform immunohistochemistry, samples were processed with VENTANA BenchMark Ultra equipment, using TGF-β3 and TGFβ-RIII antibody. Immunoexpression was evaluated by means of global cell impression. Results: TGF-β3 immunoexpression was greater in epithelial cells than in fi broblasts of patients with complete and incomplete CP; however, TGFβ-RIII immunoexpression was greater within the fi broblasts than in epithelial cells of patients with complete cleft palate. Conclusions: It was concluded that the lack of TGFβ-RIII expression in the epithelium may be related to the lack of fusion of the palatal shelves. It would be of great interest to perform a more in-depth analysis of the expressions of TGF-β3 and TGFβ-RIII within different cell populations.
Tema
Cleft palate; transforming growth factor β3; receptor III of transforming growth factor β
Idioma
spa
ISSN
ISSN: 2395-9215

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