dor_id: 60450

506.#.#.a: Público

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561.#.#.u: https://www.fmvz.unam.mx/

650.#.4.x: Biotecnología y Ciencias Agropecuarias

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

351.#.#.b: Veterinaria México OA

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

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856.4.0.u: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/373/491

100.1.#.a: Ocampo Camberos, Luis; Tapia, Graciela; Gutiérrez, Lilia; Sumano López, Héctor Salvador

524.#.#.a: Ocampo Camberos, Luis, et al. (2017). Effects of glycyrrhizic acid (Viusid-Vet® powder) on the reduction of influenza virus spread and on production parameters in pigs. Veterinaria México OA; Vol. 4 Núm. 1, 2017. Recuperado de https://repositorio.unam.mx/contenidos/60450

245.1.0.a: Effects of glycyrrhizic acid (Viusid-Vet® powder) on the reduction of influenza virus spread and on production parameters in pigs

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Medicina Veterinaria y Zootecnia, UNAM

264.#.0.c: 2017

264.#.1.c: 2017-03-22

653.#.#.a: glycyrrhizic acid; H1N1; H3N2; production; swine-influenza virus

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY 4.0 Internacional, https://creativecommons.org/licenses/by/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico vetmexicooa@gmail.com

884.#.#.k: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/373

001.#.#.#: 131.oai:ojs.pkp.sfu.ca:article/373

041.#.7.h: eng

520.3.#.a: Influenza viruses are among the most important respiratory pathogens in pigs and humans. they cause seasonal epidemics in pigs and occasional pandemics in humans. herbal remedies have been regarded as suitable elements to aid in controlling influenza. this study was carried out to analyse the effects of the in-feed administration of glycyrrhizic acid, the best-known component of liquorice (as viusid-vet® powder), in pigs suffering an outbreak of influenza. eighty crossbred duroc-landrace pigs, one day post-weaning (22 days old), were included in this trial. piglets were randomly divided into the following two groups those treated with glycyrrhizic acid and an untreated control group. serological measurements to assess viral load and humoral responses were carried out. blood samples from pigs were obtained every fortnight, starting on week two and ending on week 15. with these samples, haemagglutination inhibition (hi) tests were performed, using a/swine/new jersey/11/76 (h1n1) and a/swine/minnesota/9088-2/98 (h3n2) as reference viruses. quantitative rt-pcr tests against the m gene of the influenza virus were also performed to assess viral shedding from nasal swab samples on weeks 1 to 8 after the beginning of the trial. weight variables were assessed weekly for 18 weeks. in the hi tests, treated animals showed fewer positive responses compared to the control group for h1n1 and h3n2. however, a positive response to viral protection, as assessed by hi tests, was regarded as not conclusive of humoral immune stimulation. qrt-pcr tests for viral spread exhibited a lower rate of excretion for the treated group compared to the untreated one. hence, it appears that glycyrrhizic acid stimulates, to some extent, immune responses against pig influenza as measured by viral shedding. for mean body weight, the generalized estimating equations show a higher weight gain for pigs treated with glycyrrhizic acid than the control group (p = 0.0001). these effects may assist producers in addressing the aftermath of an influenza outbreak.figure 1. results of rt-pcr viral shedding test against the m gene. (likelihood χ21,7 = 19.2 p = 0.0001).

773.1.#.t: Veterinaria México OA; Vol. 4 Núm. 1 (2017)

773.1.#.o: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

022.#.#.a: ISSN electrónico: 2448-6760

310.#.#.a: Trimestral

264.#.1.b: Facultad de Medicina Veterinaria y Zootecnia, UNAM

doi: https://doi.org/10.21753/vmoa.4.1.373

harvesting_date: 2023-11-08 13:10:00.0

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last_modified: 2024-03-19 14:00:00

license_url: https://creativecommons.org/licenses/by/4.0/legalcode.es

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Artículo

Effects of glycyrrhizic acid (Viusid-Vet® powder) on the reduction of influenza virus spread and on production parameters in pigs

Ocampo Camberos, Luis; Tapia, Graciela; Gutiérrez, Lilia; Sumano López, Héctor Salvador

Facultad de Medicina Veterinaria y Zootecnia, UNAM, publicado en Veterinaria México OA, y cosechado de Revistas UNAM

Licencia de uso

Procedencia del contenido

Entidad o dependencia
Facultad de Medicina Veterinaria y Zootecnia, UNAM
Revista
Repositorio
Contacto
Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

Cita

Ocampo Camberos, Luis, et al. (2017). Effects of glycyrrhizic acid (Viusid-Vet® powder) on the reduction of influenza virus spread and on production parameters in pigs. Veterinaria México OA; Vol. 4 Núm. 1, 2017. Recuperado de https://repositorio.unam.mx/contenidos/60450

Descripción del recurso

Autor(es)
Ocampo Camberos, Luis; Tapia, Graciela; Gutiérrez, Lilia; Sumano López, Héctor Salvador
Tipo
Artículo de Investigación
Área del conocimiento
Biotecnología y Ciencias Agropecuarias
Título
Effects of glycyrrhizic acid (Viusid-Vet® powder) on the reduction of influenza virus spread and on production parameters in pigs
Fecha
2017-03-22
Resumen
Influenza viruses are among the most important respiratory pathogens in pigs and humans. they cause seasonal epidemics in pigs and occasional pandemics in humans. herbal remedies have been regarded as suitable elements to aid in controlling influenza. this study was carried out to analyse the effects of the in-feed administration of glycyrrhizic acid, the best-known component of liquorice (as viusid-vet® powder), in pigs suffering an outbreak of influenza. eighty crossbred duroc-landrace pigs, one day post-weaning (22 days old), were included in this trial. piglets were randomly divided into the following two groups those treated with glycyrrhizic acid and an untreated control group. serological measurements to assess viral load and humoral responses were carried out. blood samples from pigs were obtained every fortnight, starting on week two and ending on week 15. with these samples, haemagglutination inhibition (hi) tests were performed, using a/swine/new jersey/11/76 (h1n1) and a/swine/minnesota/9088-2/98 (h3n2) as reference viruses. quantitative rt-pcr tests against the m gene of the influenza virus were also performed to assess viral shedding from nasal swab samples on weeks 1 to 8 after the beginning of the trial. weight variables were assessed weekly for 18 weeks. in the hi tests, treated animals showed fewer positive responses compared to the control group for h1n1 and h3n2. however, a positive response to viral protection, as assessed by hi tests, was regarded as not conclusive of humoral immune stimulation. qrt-pcr tests for viral spread exhibited a lower rate of excretion for the treated group compared to the untreated one. hence, it appears that glycyrrhizic acid stimulates, to some extent, immune responses against pig influenza as measured by viral shedding. for mean body weight, the generalized estimating equations show a higher weight gain for pigs treated with glycyrrhizic acid than the control group (p = 0.0001). these effects may assist producers in addressing the aftermath of an influenza outbreak.figure 1. results of rt-pcr viral shedding test against the m gene. (likelihood χ21,7 = 19.2 p = 0.0001).
Tema
glycyrrhizic acid; H1N1; H3N2; production; swine-influenza virus
Idioma
eng
ISSN
ISSN electrónico: 2448-6760

Enlaces