dor_id: 23195

506.#.#.a: Público

590.#.#.d: Los artículos enviados a la "Revista Internacional de Contaminación Ambiental" se juzgan por medio de un proceso de revisión por pares

510.0.#.a: Consejo Nacional de Ciencia y Tecnología (CONACyT); Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex); Scientific Electronic Library Online (SciELO); SCOPUS, Web Of Science (WoS); Aquatic Sciences and Fisheries Abstracts, Cab Abstracts, Cab Health, Chemical Abstracts, Elsevier Biobase, Elsevier Geo Abstracts, Periódica, Pollution Abstracts, SCOPUS, Water Resources Abstracts

561.#.#.u: https://www.atmosfera.unam.mx/

650.#.4.x: Biología y Química

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: https://www.revistascca.unam.mx/rica/index.php/rica/index

351.#.#.b: Revista Internacional de Contaminación Ambiental

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

590.#.#.c: Open Journal Systems (OJS)

270.#.#.d: MX

270.1.#.d: México

590.#.#.b: Concentrador

883.#.#.u: https://revistas.unam.mx/catalogo/

883.#.#.a: Revistas UNAM

590.#.#.a: Coordinación de Difusión Cultural

883.#.#.1: https://www.publicaciones.unam.mx/

883.#.#.q: Dirección General de Publicaciones y Fomento Editorial

850.#.#.a: Universidad Nacional Autónoma de México

856.4.0.u: https://www.revistascca.unam.mx/rica/index.php/rica/article/view/RICA.2017.33.04.11/46720

100.1.#.a: Leggieri, Leonardo Ramón; de Anna, Julieta Soledad; Cerón, Gerardo Abel; Arias Darraz, Luis; Fuentes Monasterio, Daniela; Cárcamo, Juan Guillermo; Luquet, Carlos Marcelo

524.#.#.a: Leggieri, Leonardo Ramón, et al. (2017). CYPS MOLECULAR BIOMARKERS IN RAINBOW TROUT Oncorhynchus mykiss TO ASSESS OIL CONTAMINATION IN A PATAGONIAN STREAM. Revista Internacional de Contaminación Ambiental; Vol. 33 Núm. 4, 2017; 681-690. Recuperado de https://repositorio.unam.mx/contenidos/23195

245.1.0.a: CYPS MOLECULAR BIOMARKERS IN RAINBOW TROUT Oncorhynchus mykiss TO ASSESS OIL CONTAMINATION IN A PATAGONIAN STREAM

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Instituto de Ciencias de la Atmósfera y Cambio Climático, UNAM

264.#.0.c: 2017

264.#.1.c: 2017-10-30

653.#.#.a: CYP450; petroleum spill; fish; contaminated stream; Patagonia

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY-NC 4.0 Internacional, https://creativecommons.org/licenses/by-nc/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico claudio.amescua@atmosfera.unam.mx

884.#.#.k: https://www.revistascca.unam.mx/rica/index.php/rica/article/view/RICA.2017.33.04.11

001.#.#.#: 105.oai:ojs.pkp.sfu.ca:article/52469

041.#.7.h: eng

520.3.#.a: Cytochrome P450 (CYP) gene expressions were studied by semi-quantitative polymerase chain reaction (PCR) to assess oil pollution using liver and gills of juvenile rainbow trout Oncorhynchus mykiss sampled from La Mina stream (Bariloche, Argentina), up and downstream of a discharge of petroleum spill from an unproductive wellbore. Data was complemented with laboratory exposure to water accommodated fraction (WAF) from the oil spill. Oil exposure induced gill and liver CYP1A transcription (1.2-1.4-fold), which was used as reference biomarker. In both organs, CYP2K1 transcript was induced after 5 % WAF exposure, 24 h (1.8-2.0-fold), and it was down-regulated in more extended time (1.2-1.5-fold). CYP2M1 transcript levels were down-regulated in liver of impacted wild trout and in trout exposed to 5 % WAF during 96 h (1.5-1.7-fold). CYP2K1 and CYP2M1 are involved in the metabolism of fatty acids and estrogenic hormones, and its down-regulation would indicate metabolic alterations. CYP3A27 levels were only induced in liver of wild trout (1.6-fold), possibly related to crosstalk between aryl hydrocarbon receptor and pregnane X receptor signaling pathway. While CYP1A mRNA expression appears to be a more robust biomarker for detecting the effects of crude oil under different dose and exposure time, the expression of CYP2K1, CYP2M1 and CYP3A27 mRNAs would indicate different time exposure to oil pollution, particularly under high oil concentration in water. Hence, patterns of multiple CYP genes expression in rainbow trout gills and liver could be especially valuable for monitoring programs of crude oil pollution and remediation actions on Patagonian freshwater ecosystems.

773.1.#.t: Revista Internacional de Contaminación Ambiental; Vol. 33 Núm. 4 (2017); 681-690

773.1.#.o: https://www.revistascca.unam.mx/rica/index.php/rica/index

022.#.#.a: ISSN impreso: 0188-4999

310.#.#.a: Trimestral

300.#.#.a: Páginas: 681-690

264.#.1.b: Instituto de Ciencias de la Atmósfera y Cambio Climático, UNAM

doi: https://doi.org/10.20937/RICA.2017.33.04.11

harvesting_date: 2023-11-08 13:10:00.0

856.#.0.q: application/pdf

last_modified: 2024-03-19 14:00:00

license_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode.es

license_type: by-nc

_deleted_conflicts: 2-a3c53e65b8adb6caab3900f54f43ec99

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