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Ver términos de la licenciaNavarro González, Inmaculada (2013). CLONING, EXPRESSION, BIOCHEMICAL PARTIAL CHARATERIZATION AND MODELING OF ESTERASE FROM ACINETOBACTER CALCOACETICUS SP DSM587. BIOCYT Biología Ciencia y Tecnología; Vol. 6, 2013. Recuperado de https://repositorio.unam.mx/contenidos/4149477
Autor(es)
Navarro González, Inmaculada
Tipo
Artículo de Investigación
Área del conocimiento
Biología y Química
Título
CLONING, EXPRESSION, BIOCHEMICAL PARTIAL CHARATERIZATION AND MODELING OF ESTERASE FROM ACINETOBACTER CALCOACETICUS SP DSM587
Fecha
2020-06-19
Resumen
The aim of this paper has been to clone, express, purify and characterization the EstB fromAcinetobacter calcoaceticus encoded by the gen X8895. The esterase was cloned in Pet28a andpartially purified. The molecular mass of the purified enzyme was 36 kDa (by SDS) and 68.9KDa (by gel filtration chromatography). The EstB showed a maximum activity at 35ºC and pH 8and towards shorter acyl chain lengths (PNPA, PNPB, PNPC) and showed activity about Smethyltiobutanoate,too. The catalytic triad has been predicted by aminoacid sequencealignment and the structure modeling was performed used esterase 1QoR as template.
Tema
Recombinant Esterase; Over Expression; Microorganisms; Kinetic Characterization
Idioma
spa
ISSN
ISSN electrónico: 2007-2082