dor_id: 4119850
506.#.#.a: Público
590.#.#.d: Los artículos enviados a la revista "Veterinaria México OA", se juzgan por medio de un proceso de revisión por pares
510.0.#.a: Consejo Nacional de Ciencia y Tecnología (CONACyT); Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex); Scientific Electronic Library Online (SciELO); Bibliografía Latinoamericana (Biblat); La Red de Revistas Científicas de América Latina y el Caribe, España y Portugal (Redalyc); Connecting research and researchers (ORCiD)
561.#.#.u: https://www.fmvz.unam.mx/
650.#.4.x: Biotecnología y Ciencias Agropecuarias
336.#.#.b: article
336.#.#.3: Artículo de Investigación
336.#.#.a: Artículo
351.#.#.6: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index
351.#.#.b: Veterinaria México OA
351.#.#.a: Artículos
harvesting_group: RevistasUNAM
270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx
590.#.#.c: Open Journal Systems (OJS)
270.#.#.d: MX
270.1.#.d: México
590.#.#.b: Concentrador
883.#.#.u: https://revistas.unam.mx/catalogo/
883.#.#.a: Revistas UNAM
590.#.#.a: Coordinación de Difusión Cultural
883.#.#.1: https://www.publicaciones.unam.mx/
883.#.#.q: Dirección General de Publicaciones y Fomento Editorial
850.#.#.a: Universidad Nacional Autónoma de México
856.4.0.u: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/896/795
100.1.#.a: Nolasco, Eduardo; Quintana, José Antonio; Valdés, Liliana Manuela; Rangel, Lucía; Cobos Marín, Laura
524.#.#.a: Nolasco, Eduardo, et al. (2020). Attenuation of a Turkeypoxvirus field strain as an alternative to heterologous vaccination in turkeys. Veterinaria México OA; Vol. 7 Núm. 4, 2020. Recuperado de https://repositorio.unam.mx/contenidos/4119850
245.1.0.a: Attenuation of a Turkeypoxvirus field strain as an alternative to heterologous vaccination in turkeys
502.#.#.c: Universidad Nacional Autónoma de México
561.1.#.a: Facultad de Medicina Veterinaria y Zootecnia, UNAM
264.#.0.c: 2020
264.#.1.c: 2020-12-16
506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY 4.0 Internacional, https://creativecommons.org/licenses/by/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico vetmexicooa@gmail.com
884.#.#.k: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/896
001.#.#.#: 131.oai:ojs.pkp.sfu.ca:article/896
041.#.7.h: eng
520.3.#.a: Avian pox can severely impact turkey production systems. vaccination programs in México use commercially available fowlpoxvirus vaccines, that are used across different bird species. nonetheless, there are reports of sporadic disease outbreaks among vaccinated turkeys, which suggest that heterologous vaccines may provide limited immunity, presenting the need to develop homologous vaccines that can better protect turkeys. this study compared the protection granted to turkey chicks by a commercial fowlpoxvirus vaccine and by a live attenuated turkeypoxvirus vaccine after a challenge with a field isolated turkeypoxvirus virus. histopathology, polymerase chain reaction, and sequencing of dna were used for viral identification. A turkeypoxvirus strain was first isolated in chicken embryo lesions, and subsequently adapted through serial passes in chorioallantoic membrane to produce the homologous vaccine. The attenuated virus was used as a vaccine when a 104.4 embryo id50/ml titre was reached. three groups of three-week-old turkey chicks were used for challenge experiments. subjects in group 1 were immunized with the attenuated turkeypoxvirus vaccine (homologous vaccine). chicks in group 2 were vaccinated with the commercially available heterologous vaccine (fowlpoxvirus). subjects in group 3 were not vaccinated and received only saline solution (control group). two weeks after vaccination, animals from group 1 reached a 97.7 nd50 seroneutralization titre, while levels reached in group 2 birds and in control chicks were 11.7 nd50 (group 2) and zero, respectively. at this time, all groups were challenged with a suspension of a field-isolated turkeypox virus. The homologous vaccine afforded 100% protection in group 1 (10/10 individuals), while only 10% (1/10) of individuals in group 2 were protected by the commercial heterologous fowlpoxvirus vaccine. none of the non-immunized birds in group 3 were protected (0/10). these results show that the homologous vaccine afforded a greater protection against a turkeypox virus infection than that observed for the heterologous vaccine, and that a homologous vaccine can be efficiently produced by isolating and attenuating the virus from turkeypox lesions, through chorioallantoic membrane serial passes.
773.1.#.t: Veterinaria México OA; Vol. 7 Núm. 4 (2020)
773.1.#.o: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index
022.#.#.a: ISSN electrónico: 2448-6760
310.#.#.a: Trimestral
264.#.1.b: Facultad de Medicina Veterinaria y Zootecnia, UNAM
doi: https://doi.org/10.22201/fmvz.24486760e.2020.4.896
harvesting_date: 2023-11-08 13:10:00.0
856.#.0.q: application/pdf
file_creation_date: 2020-12-16 18:57:34.0
file_modification_date: 2020-12-18 01:13:07.0
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