dor_id: 4119850

506.#.#.a: Público

590.#.#.d: Los artículos enviados a la revista "Veterinaria México OA", se juzgan por medio de un proceso de revisión por pares

510.0.#.a: Consejo Nacional de Ciencia y Tecnología (CONACyT); Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex); Scientific Electronic Library Online (SciELO); Bibliografía Latinoamericana (Biblat); La Red de Revistas Científicas de América Latina y el Caribe, España y Portugal (Redalyc); Connecting research and researchers (ORCiD)

561.#.#.u: https://www.fmvz.unam.mx/

650.#.4.x: Biotecnología y Ciencias Agropecuarias

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

351.#.#.b: Veterinaria México OA

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

590.#.#.c: Open Journal Systems (OJS)

270.#.#.d: MX

270.1.#.d: México

590.#.#.b: Concentrador

883.#.#.u: https://revistas.unam.mx/catalogo/

883.#.#.a: Revistas UNAM

590.#.#.a: Coordinación de Difusión Cultural

883.#.#.1: https://www.publicaciones.unam.mx/

883.#.#.q: Dirección General de Publicaciones y Fomento Editorial

850.#.#.a: Universidad Nacional Autónoma de México

856.4.0.u: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/896/795

100.1.#.a: Nolasco, Eduardo; Quintana, José Antonio; Valdés, Liliana Manuela; Rangel, Lucía; Cobos Marín, Laura

524.#.#.a: Nolasco, Eduardo, et al. (2020). Attenuation of a Turkeypoxvirus field strain as an alternative to heterologous vaccination in turkeys. Veterinaria México OA; Vol. 7 Núm. 4, 2020. Recuperado de https://repositorio.unam.mx/contenidos/4119850

245.1.0.a: Attenuation of a Turkeypoxvirus field strain as an alternative to heterologous vaccination in turkeys

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Medicina Veterinaria y Zootecnia, UNAM

264.#.0.c: 2020

264.#.1.c: 2020-12-16

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY 4.0 Internacional, https://creativecommons.org/licenses/by/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico vetmexicooa@gmail.com

884.#.#.k: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/896

001.#.#.#: 131.oai:ojs.pkp.sfu.ca:article/896

041.#.7.h: eng

520.3.#.a: Avian pox can severely impact turkey production systems. vaccination programs in México use commercially available fowlpoxvirus vaccines, that are used across different bird species. nonetheless, there are reports of sporadic disease outbreaks among vaccinated turkeys, which suggest that heterologous vaccines may provide limited immunity, presenting the need to develop homologous vaccines that can better protect turkeys. this study compared the protection granted to turkey chicks by a commercial fowlpoxvirus vaccine and by a live attenuated turkeypoxvirus vaccine after a challenge with a field isolated turkeypoxvirus virus. histopathology, polymerase chain reaction, and sequencing of dna were used for viral identification. A turkeypoxvirus strain was first isolated in chicken embryo lesions, and subsequently adapted through serial passes in chorioallantoic membrane to produce the homologous vaccine. The attenuated virus was used as a vaccine when a 104.4 embryo id50/ml titre was reached. three groups of three-week-old turkey chicks were used for challenge experiments. subjects in group 1 were immunized with the attenuated turkeypoxvirus vaccine (homologous vaccine). chicks in group 2 were vaccinated with the commercially available heterologous vaccine (fowlpoxvirus). subjects in group 3 were not vaccinated and received only saline solution (control group). two weeks after vaccination, animals from group 1 reached a 97.7 nd50 seroneutralization titre, while levels reached in group 2 birds and in control chicks were 11.7 nd50 (group 2) and zero, respectively. at this time, all groups were challenged with a suspension of a field-isolated turkeypox virus. The homologous vaccine afforded 100% protection in group 1 (10/10 individuals), while only 10% (1/10) of individuals in group 2 were protected by the commercial heterologous fowlpoxvirus vaccine. none of the non-immunized birds in group 3 were protected (0/10). these results show that the homologous vaccine afforded a greater protection against a turkeypox virus infection than that observed for the heterologous vaccine, and that a homologous vaccine can be efficiently produced by isolating and attenuating the virus from turkeypox lesions, through chorioallantoic membrane serial passes.

773.1.#.t: Veterinaria México OA; Vol. 7 Núm. 4 (2020)

773.1.#.o: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

022.#.#.a: ISSN electrónico: 2448-6760

310.#.#.a: Trimestral

264.#.1.b: Facultad de Medicina Veterinaria y Zootecnia, UNAM

doi: https://doi.org/10.22201/fmvz.24486760e.2020.4.896

harvesting_date: 2023-11-08 13:10:00.0

856.#.0.q: application/pdf

file_creation_date: 2020-12-16 18:57:34.0

file_modification_date: 2020-12-18 01:13:07.0

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