dor_id: 4160905

506.#.#.a: Público

590.#.#.d: Los artículos enviados a "TIP Revista especializada en Ciencias químico-biológicas", se juzgan por medio de un proceso de revisión por pares

510.0.#.a: Consejo Nacional de Ciencia y Tecnología (CONACyT); Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex) Scientific Electronic Library Online (SciELO); Red de Revistas Científicas de América Latina y el Caribe, España y Portugal (Redalyc); Directory of Open Access Journals (DOAJ); Web Of Science (WoS); EBSCO, Medigraphic, Indice de Revistas Latinoamericanas en Ciencias (Periódica)

561.#.#.u: https://www.zaragoza.unam.mx/

650.#.4.x: Biología y Química

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: http://tip.zaragoza.unam.mx/index.php/tip/index

351.#.#.b: TIP Revista especializada en Ciencias Químico-Biológicas

351.#.#.a: Artículos

harvesting_group: RevistasUNAM.126

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

590.#.#.c: Open Journal Systems (OJS)

270.#.#.d: MX

270.1.#.d: México

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883.#.#.u: https://revistas.unam.mx/catalogo/

883.#.#.a: Revistas UNAM

590.#.#.a: Coordinación de Difusión Cultural

883.#.#.1: https://www.publicaciones.unam.mx/

883.#.#.q: Dirección General de Publicaciones y Fomento Editorial

850.#.#.a: Universidad Nacional Autónoma de México

856.4.0.u: http://tip.zaragoza.unam.mx/index.php/tip/article/view/663/532

100.1.#.a: de la Sota Esparza, Gastaldo Emmanuel; Alvarado Vázquez, Marco Antonio; Rivas Morales, Catalina; Rocha Estrada, Alejandra; Chávez Reyes, Arturo; Ortíz Martínez, David Mizael

524.#.#.a: de la Sota Esparza, Gastaldo Emmanuel, et al. (2024). Antidiabetic potential of extracts from Cylindropuntia imbricata (Haw.) F.M. Knuth, Opuntia engelmannii Salm-Dyck ex Engelm., Ibervillea sonorae (S. Wats.) Greene and Theobroma cacao L. TIP Revista Especializada en Ciencias Químico-Biológicas; Vol. 27, 2024. Recuperado de https://repositorio.unam.mx/contenidos/4160905

245.1.0.a: Antidiabetic potential of extracts from Cylindropuntia imbricata (Haw.) F.M. Knuth, Opuntia engelmannii Salm-Dyck ex Engelm., Ibervillea sonorae (S. Wats.) Greene and Theobroma cacao L.

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Estudios Superiores Zaragoza, UNAM

264.#.0.c: 2024

264.#.1.c: 2024-08-02

653.#.#.a: diabetes; plant extracts; α-glucosidase; DPPH; alamar blue; phytochemistry; diabetes; extractos vegetales; α-glucosidasa; DPPH; azul alamar; fitoquímica

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY-NC-ND 4.0 Internacional, https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico revistatip@yahoo.com

884.#.#.k: http://tip.zaragoza.unam.mx/index.php/tip/article/view/663

001.#.#.#: 126.oai:ojs.ojs.escire.net:article/663

041.#.7.h: spa

520.3.#.a: Diabetes mellitus is a disease that affects more than 537 million people in the world without decreasing. When diabetes becomes complicated, it damages several organs until it causes death. The drugs in use to counteract the disease produce side effects; a circumstance that has led to research on plants with anti-diabetic properties. The objective of this study was to evaluate the antidiabetic potential of extracts obtained by maceration of the following parts of the plant: Cylindropuntia imbricata (Cactaceae) cladode and seed, Opuntia engelmannii (Cactaceae) cladode and seed, Ibervillea sonorae (Cucurbitaceae) root and Theobroma cacao (Malvaceae) seed mixed with solvents of different polarity (hexane, ethyl acetate, dichloromethane and methanol). A total of 24 extracts were obtained and subjected to the following analyses: 1) phytochemical screening to determine their composition, 2) toxicity in B16F10 cells using the alamar blue test, 3) antioxidant capacity through DPPH inhibition, and 4) in vitro evaluation to determine their antihyperglycemic capacity (inhibition of alpha-glucosidase). The results obtained from methanolic extracts with O. engelmannii and T. cacao seeds, as well as ethyl acetate extracts with T. cacao and C. imbricata seeds showed antioxidant and antihyperglycemic activity. No toxicity in B16F10 cells, and antidiabetic potential in vitro.

773.1.#.t: TIP Revista Especializada en Ciencias Químico-Biológicas; Vol. 27 (2024)

773.1.#.o: http://tip.zaragoza.unam.mx/index.php/tip/index

022.#.#.a: ISSN electrónico: 2395-8723; ISSN impreso: 1405-888X

310.#.#.a: Publicación contínua

599.#.#.a: 126

264.#.1.b: Facultad de Estudios Superiores Zaragoza, UNAM

doi: https://doi.org/10.22201/fesz.23958723e.2024.663

handle: 00f0f4c2e626360a

harvesting_date: 2024-11-01 00:00:00.0

856.#.0.q: application/pdf

file_creation_date: 2024-08-01 23:06:52.0

file_modification_date: 2024-08-01 17:06:53.0

file_name: 96cf3096fd3832361c247a929239804f80822d11093097f25a117292573a3d9d.pdf

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file_size: 1235016

245.1.0.b: Potencial antidiabético de extractos de Cylindropuntia imbricata (Haw.) F. M. Knuth, Opuntia engelmannii Salm-Dyck ex Engelm., Ibervillea sonorae (S. Wats.) Greene y Theobroma cacao L.

last_modified: 2024-11-01 00:00:00

license_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es

license_type: by-nc-nd

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Artículo

Antidiabetic potential of extracts from Cylindropuntia imbricata (Haw.) F.M. Knuth, Opuntia engelmannii Salm-Dyck ex Engelm., Ibervillea sonorae (S. Wats.) Greene and Theobroma cacao L.

de la Sota Esparza, Gastaldo Emmanuel; Alvarado Vázquez, Marco Antonio; Rivas Morales, Catalina; Rocha Estrada, Alejandra; Chávez Reyes, Arturo; Ortíz Martínez, David Mizael

Facultad de Estudios Superiores Zaragoza, UNAM, publicado en TIP Revista especializada en Ciencias Químico-Biológicas, y cosechado de Revistas UNAM

Licencia de uso

Procedencia del contenido

Cita

de la Sota Esparza, Gastaldo Emmanuel, et al. (2024). Antidiabetic potential of extracts from Cylindropuntia imbricata (Haw.) F.M. Knuth, Opuntia engelmannii Salm-Dyck ex Engelm., Ibervillea sonorae (S. Wats.) Greene and Theobroma cacao L. TIP Revista Especializada en Ciencias Químico-Biológicas; Vol. 27, 2024. Recuperado de https://repositorio.unam.mx/contenidos/4160905

Descripción del recurso

Autor(es)
de la Sota Esparza, Gastaldo Emmanuel; Alvarado Vázquez, Marco Antonio; Rivas Morales, Catalina; Rocha Estrada, Alejandra; Chávez Reyes, Arturo; Ortíz Martínez, David Mizael
Tipo
Artículo de Investigación
Área del conocimiento
Biología y Química
Título
Antidiabetic potential of extracts from Cylindropuntia imbricata (Haw.) F.M. Knuth, Opuntia engelmannii Salm-Dyck ex Engelm., Ibervillea sonorae (S. Wats.) Greene and Theobroma cacao L.
Fecha
2024-08-02
Resumen
Diabetes mellitus is a disease that affects more than 537 million people in the world without decreasing. When diabetes becomes complicated, it damages several organs until it causes death. The drugs in use to counteract the disease produce side effects; a circumstance that has led to research on plants with anti-diabetic properties. The objective of this study was to evaluate the antidiabetic potential of extracts obtained by maceration of the following parts of the plant: Cylindropuntia imbricata (Cactaceae) cladode and seed, Opuntia engelmannii (Cactaceae) cladode and seed, Ibervillea sonorae (Cucurbitaceae) root and Theobroma cacao (Malvaceae) seed mixed with solvents of different polarity (hexane, ethyl acetate, dichloromethane and methanol). A total of 24 extracts were obtained and subjected to the following analyses: 1) phytochemical screening to determine their composition, 2) toxicity in B16F10 cells using the alamar blue test, 3) antioxidant capacity through DPPH inhibition, and 4) in vitro evaluation to determine their antihyperglycemic capacity (inhibition of alpha-glucosidase). The results obtained from methanolic extracts with O. engelmannii and T. cacao seeds, as well as ethyl acetate extracts with T. cacao and C. imbricata seeds showed antioxidant and antihyperglycemic activity. No toxicity in B16F10 cells, and antidiabetic potential in vitro.
Tema
diabetes; plant extracts; α-glucosidase; DPPH; alamar blue; phytochemistry; diabetes; extractos vegetales; α-glucosidasa; DPPH; azul alamar; fitoquímica
Idioma
spa
ISSN
ISSN electrónico: 2395-8723; ISSN impreso: 1405-888X

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