dor_id: 4149033

506.#.#.a: Público

590.#.#.d: Los artículos enviados a la revista "Veterinaria México OA", se juzgan por medio de un proceso de revisión por pares

510.0.#.a: Consejo Nacional de Ciencia y Tecnología (CONACyT); Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex); Scientific Electronic Library Online (SciELO); Bibliografía Latinoamericana (Biblat); La Red de Revistas Científicas de América Latina y el Caribe, España y Portugal (Redalyc); Connecting research and researchers (ORCiD)

561.#.#.u: https://www.fmvz.unam.mx/

650.#.4.x: Biotecnología y Ciencias Agropecuarias

336.#.#.b: article

336.#.#.3: Artículo de Investigación

336.#.#.a: Artículo

351.#.#.6: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

351.#.#.b: Veterinaria México OA

351.#.#.a: Artículos

harvesting_group: RevistasUNAM

270.1.#.p: Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx

590.#.#.c: Open Journal Systems (OJS)

270.#.#.d: MX

270.1.#.d: México

590.#.#.b: Concentrador

883.#.#.u: https://revistas.unam.mx/catalogo/

883.#.#.a: Revistas UNAM

590.#.#.a: Coordinación de Difusión Cultural

883.#.#.1: https://www.publicaciones.unam.mx/

883.#.#.q: Dirección General de Publicaciones y Fomento Editorial

850.#.#.a: Universidad Nacional Autónoma de México

856.4.0.u: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/1130/893

100.1.#.a: Gutiérrez, Lilia; Sumano, Héctor; Ocampo, Luis; Nieto, Agustín; Aquino, Itzcoatl

524.#.#.a: Gutiérrez, Lilia, et al. (2023). A pharmacological perspective on the use of Benzylpenicillin-G in the production of veterinary medicine in Latin America. Veterinaria México OA; Vol. 10, 2023. Recuperado de https://repositorio.unam.mx/contenidos/4149033

245.1.0.a: A pharmacological perspective on the use of Benzylpenicillin-G in the production of veterinary medicine in Latin America

502.#.#.c: Universidad Nacional Autónoma de México

561.1.#.a: Facultad de Medicina Veterinaria y Zootecnia, UNAM

264.#.0.c: 2023

264.#.1.c: 2023-03-06

653.#.#.a: Bencylpenicillin-G; pharmacokinetics/pharmacodynamics; antibacterial resistance; commercial preparations; Veterinary Medicine

506.1.#.a: La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY 4.0 Internacional, https://creativecommons.org/licenses/by/4.0/legalcode.es, para un uso diferente consultar al responsable jurídico del repositorio por medio del correo electrónico vetmexicooa@gmail.com

884.#.#.k: https://veterinariamexico.fmvz.unam.mx/index.php/vet/article/view/1130

001.#.#.#: 131.oai:ojs.pkp.sfu.ca:article/1130

041.#.7.h: eng

520.3.#.a: Benzylpenicillin-g (bp-g) is one of human and veterinary medicine’s most widely used antibacterial drugs. it represents a large market for the phar­maceutical industry, and various combinations with frail pharmacological support have been made available to veterinarians. The crystalline sodium and potassium salts of bp-g and the benzathine salt of bp-g have been incorporated into many existing preparations, arguing that higher and more prolonged concentrations are obtained. however, there are not evidence published. notwithstanding the above, these preparations are presented as sustained-release ones and capable of achieving therapeutic concentrations. Thereare no pharmacokinetic bases for such combinations of bp-g deriva­tives. it is unlikely that such combinations provide better serum profiles than those offered by an adequate dose of only procaine bp-g. The incorporation of the bp-g benzathine is prohibited in many countries. in latin america, such combinations limit the amount of procaine bp-g that should be in­jected, ideally ≥ 20 000 iu/kg of body weight every 12-24 h. within the framework of the rational use of antimicrobial drugs in veterinary medicine advanced by the world health organization (who) and based on pharma­cological considerations, it is proposed that combinations of bp-g derivatives be restricted, allowing only bp-g procaine preparations. also, formulations of bp-g incorporating other active principles should offer solid pharmacological support. to date, combined preparations of bp-g have shown no formal pharmacological support. based on the information presented in this review, it is feasible to conclude that the only bp-g derivative that should be available for veterinary medicine is procaine bp-g.

773.1.#.t: Veterinaria México OA; Vol. 10 (2023)

773.1.#.o: https://veterinariamexico.fmvz.unam.mx/index.php/vet/index

022.#.#.a: ISSN electrónico: 2448-6760

310.#.#.a: Trimestral

264.#.1.b: Facultad de Medicina Veterinaria y Zootecnia, UNAM

doi: https://doi.org/10.22201/fmvz.24486760e.2023.1130

harvesting_date: 2023-11-08 13:10:00.0

856.#.0.q: application/pdf

file_creation_date: 2023-03-15 22:26:56.0

file_modification_date: 2023-03-15 22:27:05.0

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