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Facultad de Medicina Veterinaria y Zootecnia, UNAM
Revista
Repositorio
Contacto
Revistas UNAM. Dirección General de Publicaciones y Fomento Editorial, UNAM en revistas@unam.mx
Nevzat Emre, Aslan, et al. (2024). Efficiency of ozone (O3) therapy on experimental acidic skin burns in rats. Veterinaria México OA; Vol. 11, 2024. Recuperado de https://repositorio.unam.mx/contenidos/4158521
Autor(es)
Nevzat Emre, Aslan; Erol, Hanifi; Balcıoğlu, Esra; Betül, Yalçin
Tipo
Artículo de Investigación
Área del conocimiento
Biotecnología y Ciencias Agropecuarias
Título
Efficiency of ozone (O3) therapy on experimental acidic skin burns in rats
Fecha
2024-02-14
Resumen
In this study, it was aimed to investigate the efficacy of O3 therapy in experimentally induced HF skin burns in rats. A total of 20 healthy male Wistar Albino rats (weighing 250-300 g, aged 16 weeks) were used as the material of the study. They were divided into two groups (as experimental and control groups) of 10 rats which were housed individually and fed ad libitum. Hydrofluoric acid (HF) skin burns were induced in all animals. The ozonized (20 µg O3/mL) liquid vaseline was applied topically for seven days to the experiment group as well as parallelly, a saline solution was applied to the control group. In the histopathologic evaluation, inflammation, vascularization, epithelial regeneration and fibrosis were evaluated. The epithelial proliferation and collagenization were higher and statistically significant in the experimental group, while the infiltration was higher and statistically significant in the control group. As a result of this study, it was observed that ozone plays an important role in the tissue repair process in chemical burns. The increase of fibroblast activation and re-epithelization in the experimental group demonstrated that ozone therapy could be suggested as first aid in HF skin burns. It was concluded that more studies on ozone are needed to shed light on the subject.
Tema
Hydrofluoric Acid (hf); Ozone; Wistar Albino Rats; Fibroblast Activation; Veterinary Medicine; Veterinary Dermathology
Idioma
eng
ISSN
ISSN electrónico: 2448-6760
